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Anecdotal evidence from patients using Spironolactone provides a more personal perspective on its effects on hair health. These reports range widely, with some patients experiencing noticeable improvements in hair thickness and growth, especially in cases of hormonal-related hair loss. Interestingly, Spironolactone has also been explored as a treatment for certain types of hair loss, particularly those linked to hormonal imbalances, like androgenetic alopecia.
It takes at least six months to see results

But because spironolactone has the opposite effect, it’s called a potassium-sparing diuretic. Eating lots of potassium-rich foods while taking spironolactone can also increase your risk for hyperkalemia. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe. Spironolactone oral tablets can interact with several other medications.
Other side effects
These include hyperkalemia (high potassium level), breast tenderness, and menstrual irregularities. Because spironolactone is an anti-androgen drug, it’s used to treat women whose hair loss has hormonal (specifically, androgenic) causes (Azarchi, 2019; Goldstein, 2022). Your provider can easily check to see if your androgen levels are off with a simple blood test.
Response and effectiveness
Instead, your doctor will prescribe the lowest dosage that best manages your blood pressure and potassium level. Topical minoxidil is an FDA-approved treatment that is used to combat the effects of androgenetic alopecia, and it’s highly effective at promoting the regrowth of hair, according to a 2019 study. It can be purchased over the counter, and it’s found in various strengths — typically 2% to 5%, Agbai says.
Signs of drug-induced alopecia
Talk to your doctor before taking any other medications while taking spironolactone. That includes nutritional supplements (especially potassium) and diuretics. Follow up with your doctor after taking spironolactone for six months. Depending on your results, they might increase your dosage or prescribe a different medication to take with or instead of spironolactone.
When your Vyvanse dose is too low
It comes with serious risks if you don’t take it as prescribed. Examples of drugs that can cause interactions with spironolactone are listed below. It comes as an oral tablet and an oral suspension (a kind of liquid mixture). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
For excessive aldosterone secretion
I still have my period but it was now coming twice a month (one light, one heavy) and I was getting cramps which I have not had in years. I've never had issues or irregularities with my period, it is always on time, every month. Yes, I now believe it's the drug and like the other members, I have been told by my derm that Spiro is not the cause because it actually helps with hair loss. This is my story below and it mirrors everyone else here. For a full list see the leaflet inside your medicines packet.
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Using potassium-containing salt substitutes can cause your potassium level to become too high. Spironolactone helps your body to get rid of excess fluid. For example, if you take spironolactone for heart failure or edema (fluid retention and swelling) you’re likely to lose weight as your body gets rid of excess fluid. Serious side effects from spironolactone oral tablets aren’t common, but they can occur.
Serious side effects of spironolactone
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If you’re not sure if you’ll need to get prior authorization for spironolactone oral tablets, contact your insurance company. As with all medications, the cost of spironolactone oral tablets can vary. The actual price you’ll pay depends on your insurance plan, your location, and the pharmacy you use. To learn more about the cost of spironolactone, refer to this article. With primary hyperaldosteronism, your adrenal glands produce too much of a hormone called aldosterone. It may be passed down in families, or it may be caused by a tumor or growth on your adrenal glands.
However, its role in hair loss is nuanced, warranting a closer look into how it affects hair growth and shedding. To conduct a systematic review evaluating the efficacy and safety of topical and oral spironolactone in AGA treatment. In most cases, hair growth returns to its previous state once you’ve stopped taking a medication that causes hair loss. Adjusting the dosage may also ease symptoms of hair loss.
They can tell you about other medications that may work well for you. It’s not known how often kidney problems occur with spironolactone. But you may have a higher risk for kidney problems if you have low blood pressure or become dehydrated during treatment. (With dehydration, you have a low fluid level in your body.) Spironolactone makes your body lose fluid, so you’re more likely to have low blood pressure or become dehydrated with the drug. Because spironolactone “blocks” aldosterone, giving spironolactone to someone with adrenal insufficiency risks potentially hazardous high blood potassium and low blood pressure. In case you haven't heard of this buzzy oral medication, touted for its acne-tackling abilities, spironolactone was initially developed as a diuretic for high blood pressure.
You will need to consult a medical provider to know exactly what is causing your hair loss, and they can then determine the right treatment for that condition. In the study, after using spironolactone, more than 74% of patients showed signs of improvement or stability in regard to hair loss. In this article, we’ll explore what spironolactone (Aldactone) is and how it works to help with hair loss. We’ll also discuss any side effects you need to be aware of and who should not be taking the medication.
Spironolactone can sometimes cause sexual problems, such as reduced sex drive and erectile dysfunction. These side effects could possibly lead to emotional problems in some people. Emotional side effects weren’t reported in people who took spironolactone during clinical studies. There’s not an FDA-approved dosage of spironolactone for acne, because acne isn’t an approved use for this drug.
Don’t take two doses together to make up for missing a dose. Spironolactone is used to treat primary hyperaldosteronism (a condition in which your adrenal glands produce too much of the hormone aldosterone). The usual dosage for edema ranges from 25 mg to 200 mg per day. A typical starting dosage for this use is 100 mg per day. Your doctor may adjust your dosage as needed during treatment.
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